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Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides
Cancer cells exhibit a dynamic metabolic landscape and require a sufficient supply of nucleotides and other macromolecules to grow and proliferate. To meet the metabolic requirements for cell growth, cancer cells must stimulate de novo nucleotide synthesis to obtain adequate nucleotide pools to supp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562601/ https://www.ncbi.nlm.nih.gov/pubmed/31108873 http://dx.doi.org/10.3390/cancers11050688 |