Amino Acid Deprivation-Induced Autophagy Requires Upregulation of DIRAS3 through Reduction of E2F1 and E2F4 Transcriptional Repression

Failure to cure ovarian cancer relates to the persistence of dormant, drug-resistant cancer cells following surgery and chemotherapy. “Second look” surgery can detect small, poorly vascularized nodules of persistent ovarian cancer in ~50% of patients, where >80% are undergoing autophagy and expre...

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Detalles Bibliográficos
Autores principales: Sutton, Margie N., Huang, Gilbert Y., Zhou, Jinhua, Mao, Weiqun, Langley, Robert, Lu, Zhen, Bast, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562629/
https://www.ncbi.nlm.nih.gov/pubmed/31052266
http://dx.doi.org/10.3390/cancers11050603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562629/
https://www.ncbi.nlm.nih.gov/pubmed/31052266
http://dx.doi.org/10.3390/cancers11050603

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