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Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion

Endoplasmic reticulum (ER) proteostasis is often altered in tumor cells due to intrinsic (oncogene expression, aneuploidy) and extrinsic (environmental) challenges. ER stress triggers the activation of an adaptive response named the Unfolded Protein Response (UPR), leading to protein translation rep...

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Detalles Bibliográficos
Autores principales: Limia, Celia Maria, Sauzay, Chloé, Urra, Hery, Hetz, Claudio, Chevet, Eric, Avril, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562633/
https://www.ncbi.nlm.nih.gov/pubmed/31064137
http://dx.doi.org/10.3390/cancers11050631