Preserved Cerebral Oxygen Metabolism in Astrocytic Dysfunction: A Combination Study of (15)O-Gas PET with (14)C-Acetate Autoradiography

Fluorocitrate (FC) is a specific metabolic inhibitor of the tricarboxylic acid (TCA) cycle in astrocytes. The purpose of this study was to evaluate whether inhibition of the astrocyte TCA cycle by FC would affect the oxygen metabolism in the rat brain. At 4 h after the intracranial FC injection, the...

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Detalles Bibliográficos
Autores principales: Macaisa, Carla Mari, Watabe, Tadashi, Liu, Yuwei, Romanov, Victor, Kanai, Yasukazu, Horitsugi, Genki, Kato, Hiroki, Shimosegawa, Eku, Hatazawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562644/
https://www.ncbi.nlm.nih.gov/pubmed/31058865
http://dx.doi.org/10.3390/brainsci9050101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562644/
https://www.ncbi.nlm.nih.gov/pubmed/31058865
http://dx.doi.org/10.3390/brainsci9050101

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