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Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer

The Hedgehog/GLI signaling pathway plays an important role in normal embryonic tissue development and has been implicated in the pathogenesis of various human cancers. In this review article, we summarize pre-clinical evidence supporting the suitability of targeting this signaling pathway in cancers...

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Detalles Bibliográficos
Autores principales: Xie, Hao, Paradise, Brooke D., Ma, Wen Wee, Fernandez-Zapico, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562674/
https://www.ncbi.nlm.nih.gov/pubmed/31035664
http://dx.doi.org/10.3390/cells8050394