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Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer
The Hedgehog/GLI signaling pathway plays an important role in normal embryonic tissue development and has been implicated in the pathogenesis of various human cancers. In this review article, we summarize pre-clinical evidence supporting the suitability of targeting this signaling pathway in cancers...
Autores principales: | Xie, Hao, Paradise, Brooke D., Ma, Wen Wee, Fernandez-Zapico, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562674/ https://www.ncbi.nlm.nih.gov/pubmed/31035664 http://dx.doi.org/10.3390/cells8050394 |
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