Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in Dictyostelium discoideum Suggests That Cytopathological Outcomes Result from Altered TOR Signalling

The neuronal ceroid lipofuscinoses comprise a group of neurodegenerative disorders with similar clinical manifestations whose precise mechanisms of disease are presently unknown. We created multiple cell lines each with different levels of reduction of expression of the gene coding for the type 2 va...

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Detalles Bibliográficos
Autores principales: Smith, Paige K., Sen, Melodi G., Fisher, Paul R., Annesley, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562681/
https://www.ncbi.nlm.nih.gov/pubmed/31100984
http://dx.doi.org/10.3390/cells8050469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562681/
https://www.ncbi.nlm.nih.gov/pubmed/31100984
http://dx.doi.org/10.3390/cells8050469

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