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Tumour-Derived Laminin α5 (LAMA5) Promotes Colorectal Liver Metastasis Growth, Branching Angiogenesis and Notch Pathway Inhibition

Hepatic metastatic growth is dependent upon stromal factors including the matrisomal proteins that make up the extracellular matrix (ECM). Laminins are ECM glycoproteins with several functions relevant to tumour progression including angiogenesis. We investigated whether metastatic colon cancer cell...

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Detalles Bibliográficos
Autores principales: Gordon-Weeks, Alex, Lim, Su Yin, Yuzhalin, Arseniy, Lucotti, Serena, Vermeer, Jenny Adriana Francisca, Jones, Keaton, Chen, Jianzhou, Muschel, Ruth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562694/
https://www.ncbi.nlm.nih.gov/pubmed/31064120
http://dx.doi.org/10.3390/cancers11050630