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NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes

Uptake of glutamate from the extracellular space and glutamate release to neurons are two major processes conducted by astrocytes in the central nervous system (CNS) that protect against glutamate excitotoxicity and strengthen neuronal firing, respectively. During inflammatory conditions in the CNS,...

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Detalles Bibliográficos
Autores principales: Mahmoud, Shaimaa, Gharagozloo, Marjan, Simard, Camille, Amrani, Abdelaziz, Gris, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562695/
https://www.ncbi.nlm.nih.gov/pubmed/31052241
http://dx.doi.org/10.3390/cells8050400