Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation

The 18 kDa translocator protein (TSPO) ligands 2-Cl-MGV-1 and MGV-1 can attenuate cell death of astrocyte-like cells (U118MG) and induce differentiation of neuronal progenitor cells (PC-12). Lipopolysaccharide (LPS) is a bacterial membrane endotoxin that activates cellular inflammatory pathways by r...

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Detalles Bibliográficos
Autores principales: Monga, Sheelu, Nagler, Rafi, Amara, Rula, Weizman, Abraham, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562711/
https://www.ncbi.nlm.nih.gov/pubmed/31121852
http://dx.doi.org/10.3390/cells8050486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562711/
https://www.ncbi.nlm.nih.gov/pubmed/31121852
http://dx.doi.org/10.3390/cells8050486

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