mTOR Inhibitors Can Enhance the Anti-Tumor Effects of DNA Vaccines through Modulating Dendritic Cell Function in the Tumor Microenvironment

The life span of dendritic cells (DCs) can become short following induced activation, which is associated with metabolic transition due to the regulation of mechanistic target of rapamycin (mTOR). The purpose of this study was to investigate the potential of inhibiting mTOR to modulate DC functions...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Li, Lin, Han-Wei, Sun, Nai-Yun, Yie, Jr-Chi, Hung, Hsueh-Chih, Chen, Chi-An, Sun, Wei-Zen, Cheng, Wen-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562783/
https://www.ncbi.nlm.nih.gov/pubmed/31052575
http://dx.doi.org/10.3390/cancers11050617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562783/
https://www.ncbi.nlm.nih.gov/pubmed/31052575
http://dx.doi.org/10.3390/cancers11050617

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