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Endoplasmic Reticulum Detergent-Resistant Membranes Accommodate Hepatitis C Virus Proteins for Viral Assembly

During Hepatitis C virus (HCV) morphogenesis, the non-structural protein 2 (NS2) brings the envelope proteins 1 and 2 (E1, E2), NS3, and NS5A together to form a complex at the endoplasmic reticulum (ER) membrane, initiating HCV assembly. The nature of the interactions in this complex is unclear, but...

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Detalles Bibliográficos
Autores principales: Boyer, Audrey, Dreneau, Julie, Dumans, Amélie, Burlaud-Gaillard, Julien, Bull-Maurer, Anne, Roingeard, Philippe, Meunier, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562800/
https://www.ncbi.nlm.nih.gov/pubmed/31121874
http://dx.doi.org/10.3390/cells8050487