Targeting Endometrial Cancer Stem Cell Activity with Metformin Is Inhibited by Patient-Derived Adipocyte-Secreted Factors

Advanced endometrial cancer continues to have a poor prognosis, due to limited treatment options, which may be further adversely impacted by obesity. Endometrial cancer stem cells have been reported to drive metastasis, chemotherapy resistance and disease relapse, but have yet to be fully characteri...

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Detalles Bibliográficos
Autores principales: Kitson, Sarah J., Rosser, Matthew, Fischer, Deborah P., Marshall, Kay M., Clarke, Robert B., Crosbie, Emma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562824/
https://www.ncbi.nlm.nih.gov/pubmed/31083574
http://dx.doi.org/10.3390/cancers11050653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562824/
https://www.ncbi.nlm.nih.gov/pubmed/31083574
http://dx.doi.org/10.3390/cancers11050653

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