Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Fas(lpr) Mice

SH3 domain-binding protein 2 (SH3BP2) is an adaptor protein that is predominantly expressed in immune cells, and it regulates intracellular signaling. We had previously reported that a gain-of-function mutation in SH3BP2 exacerbates inflammation and bone loss in murine arthritis models. Here, we exp...

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Detalles Bibliográficos
Autores principales: Nagasu, Akiko, Mukai, Tomoyuki, Iseki, Masanori, Kawahara, Kyoko, Tsuji, Shoko, Nagasu, Hajime, Ueki, Yasuyoshi, Ishihara, Katsuhiko, Kashihara, Naoki, Morita, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562867/
https://www.ncbi.nlm.nih.gov/pubmed/31052273
http://dx.doi.org/10.3390/cells8050402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562867/
https://www.ncbi.nlm.nih.gov/pubmed/31052273
http://dx.doi.org/10.3390/cells8050402

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