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From Normal to Obesity and Back: The Associations between Mitochondrial DNA Copy Number, Gender, and Body Mass Index

Mitochondrial DNA (mtDNA) encodes core subunits of oxidative phosphorylation complexes and, as a result of intricate regulatory crosstalk between nuclear and mitochondrial genomes, the total number of mtDNA copies fits the requirements of each cell type. Deviations from the physiological number of m...

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Detalles Bibliográficos
Autores principales: Skuratovskaia, Daria, Litvinova, Larisa, Vulf, Maria, Zatolokin, Pavel, Popadin, Konstantin, Mazunin, Ilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562937/
https://www.ncbi.nlm.nih.gov/pubmed/31075887
http://dx.doi.org/10.3390/cells8050430