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Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity

Xenobiotic-metabolizing enzymes (XME) mediate the body’s response to potentially harmful compounds of exogenous/endogenous origin to which individuals are exposed during their lifetime. Aging adversely affects such responses, making the elderly more susceptible to toxics. Of note, XME genetic variab...

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Detalles Bibliográficos
Autores principales: Crocco, Paolina, Montesanto, Alberto, Dato, Serena, Geracitano, Silvana, Iannone, Francesca, Passarino, Giuseppe, Rose, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562959/
https://www.ncbi.nlm.nih.gov/pubmed/31137904
http://dx.doi.org/10.3390/genes10050403