Cargando…

Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

Members of the lysyl oxidase (LOX) family are secreted copper-dependent amine oxidases that catalyze the covalent crosslinking of collagens and elastin in the extracellular matrix (ECM), an essential process for the structural integrity of all tissues. LOX enzymes can also remodel the tumor microenv...

Descripción completa

Detalles Bibliográficos
Autores principales: Amendola, Pier Giorgio, Reuten, Raphael, Erler, Janine Terra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562985/
https://www.ncbi.nlm.nih.gov/pubmed/31130685
http://dx.doi.org/10.3390/cancers11050729