Protective Role of Hepcidin in Polymicrobial Sepsis and Acute Kidney Injury

Background: Acute kidney injury (AKI) portends worse prognosis following sepsis, with limited available interventions. Host iron acquisition by pathogens and systemic inflammatory response are key events in the pathogenesis of sepsis. In sepsis, hepcidin induces iron sequestration to limit iron avai...

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Detalles Bibliográficos
Autores principales: Scindia, Yogesh, Wlazlo, Ewa, Leeds, Joseph, Loi, Valentina, Ledesma, Jonathan, Cechova, Sylvia, Ghias, Elizabeth, Swaminathan, Sundararaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563000/
https://www.ncbi.nlm.nih.gov/pubmed/31244655
http://dx.doi.org/10.3389/fphar.2019.00615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563000/
https://www.ncbi.nlm.nih.gov/pubmed/31244655
http://dx.doi.org/10.3389/fphar.2019.00615

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