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An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis

White adipose tissue (WAT) lipolysis contributes to energy balance during fasting. Lipolysis can proceed by the sequential hydrolysis of triglycerides (TGs) by adipose triglyceride lipase (ATGL), then of diacylglycerols (DGs) by hormone-sensitive lipase (HSL). We showed that the combined genetic def...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Zhang, Cong Cong, Yang, Hao, Soni, Krishnakant G., Wang, Shu Pei, Mitchell, Grant A., Wu, Jiang Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563012/
https://www.ncbi.nlm.nih.gov/pubmed/31035700
http://dx.doi.org/10.3390/cells8050395