Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are involved in fast synaptic transmission and mediated physiological activities in the nervous system. α-Conotoxin ImI exhibits subtype-specific blockade towards homomeric α7 and α9 receptors. In this study, we establishe...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoxiao, Liang, Jiazhen, Zhang, Zheyu, Jiang, Tao, Yu, Rilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563025/
https://www.ncbi.nlm.nih.gov/pubmed/31126085
http://dx.doi.org/10.3390/md17050303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563025/
https://www.ncbi.nlm.nih.gov/pubmed/31126085
http://dx.doi.org/10.3390/md17050303

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