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Blockade of Human α7 Nicotinic Acetylcholine Receptor by α-Conotoxin ImI Dendrimer: Insight from Computational Simulations

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are involved in fast synaptic transmission and mediated physiological activities in the nervous system. α-Conotoxin ImI exhibits subtype-specific blockade towards homomeric α7 and α9 receptors. In this study, we establishe...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaoxiao, Liang, Jiazhen, Zhang, Zheyu, Jiang, Tao, Yu, Rilei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563025/ https://www.ncbi.nlm.nih.gov/pubmed/31126085 http://dx.doi.org/10.3390/md17050303

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