Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy

The so-called immune checkpoints are pathways that regulate the timing and intensity of the immune response to avoid an excessive reaction and to protect the host from autoimmunity. Immune checkpoint inhibitors (ICIs) are designed to target the negative regulatory pathways of T cells, and they have...

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Detalles Bibliográficos
Autores principales: Lecis, Daniele, Sangaletti, Sabina, Colombo, Mario P., Chiodoni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563035/
https://www.ncbi.nlm.nih.gov/pubmed/31060225
http://dx.doi.org/10.3390/cancers11050624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563035/
https://www.ncbi.nlm.nih.gov/pubmed/31060225
http://dx.doi.org/10.3390/cancers11050624

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