Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma

DNA somatic copy number aberrations (SCNAs) are key drivers in oesophagogastric adenocarcinoma (OGA). Whether minimally invasive SCNA analysis of circulating tumour (ct)DNA can predict treatment outcomes and reveal how SCNAs evolve during chemotherapy is unknown. We investigated this by low-coverage...

Descripción completa

Detalles Bibliográficos
Autores principales: Davidson, Michael, Barber, Louise J., Woolston, Andrew, Cafferkey, Catherine, Mansukhani, Sonia, Griffiths, Beatrice, Moorcraft, Sing-Yu, Rana, Isma, Begum, Ruwaida, Assiotis, Ioannis, Matthews, Nik, Rao, Sheela, Watkins, David, Chau, Ian, Cunningham, David, Starling, Naureen, Gerlinger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563045/
https://www.ncbi.nlm.nih.gov/pubmed/31137920
http://dx.doi.org/10.3390/cancers11050736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563045/
https://www.ncbi.nlm.nih.gov/pubmed/31137920
http://dx.doi.org/10.3390/cancers11050736

Ejemplares similares