Involvement of TREK-1 Channel in Cell Viability of H9c2 Rat Cardiomyoblasts Affected by Bupivacaine and Lipid Emulsion

Lipid emulsion (LE) therapy has been used to reduce overdose of bupivacaine (BPV)-induced cardiotoxicity. The TWIK-related potassium channel-1 (TREK-1) is inhibited by BPV and activated by polyunsaturated fatty acids, which are the main component in LE. These pharmacological properties inspired us t...

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Detalles Bibliográficos
Autores principales: Yang, Jun Ho, Siregar, Adrian S., Kim, Eun-Jin, Nyiramana, Marie Merci, Shin, Eui-Jung, Han, Jaehee, Sohn, Ju-Tae, Kim, Jong Woo, Kang, Dawon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563050/
https://www.ncbi.nlm.nih.gov/pubmed/31091801
http://dx.doi.org/10.3390/cells8050454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563050/
https://www.ncbi.nlm.nih.gov/pubmed/31091801
http://dx.doi.org/10.3390/cells8050454

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