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Regions of homozygosity as risk factors for multiple myeloma

Genomic regions of homozygosity (ROH), detectable in outbred populations, have been implicated as determinants of inherited risk. To examine whether ROH is associated with risk of multiple myeloma (MM), we performed whole‐genome homozygosity analysis using single‐nucleotide polymorphism genotype dat...

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Detalles Bibliográficos
Autores principales: Went, Molly, Sud, Amit, Li, Ni, Johnson, David C., Mitchell, Jonathan S., Kaiser, Martin, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563058/
https://www.ncbi.nlm.nih.gov/pubmed/30768683
http://dx.doi.org/10.1111/ahg.12304