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Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine

BACKGROUND: Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as addiction liability. Ligands that discriminate between the different isotypes of nicotinic acetylcholine receptors (...

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Detalles Bibliográficos
Autores principales: Schapira, Matthieu, Abagyan, Ruben, Totrov, Maxim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65631/
https://www.ncbi.nlm.nih.gov/pubmed/11860617
http://dx.doi.org/10.1186/1472-6807-2-1