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c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis

Casitas B lineage lymphoma (c-Cbl) is a multifunctional protein with a ubiquitin E3 ligase activity capable of degrading diverse sets of proteins. Although previous work had focused mainly on c-Cbl mutations in humans with hematological malignancies, recent emerging evidence suggests a critical role...

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Detalles Bibliográficos
Autores principales: Lyle, Chimera L., Belghasem, Mostafa, Chitalia, Vipul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563115/
https://www.ncbi.nlm.nih.gov/pubmed/31126146
http://dx.doi.org/10.3390/cells8050498