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Telomere Gene Therapy: Polarizing Therapeutic Goals for Treatment of Various Diseases

Modulation of telomerase maintenance by gene therapy must meet two polarizing requirements to achieve different therapeutic outcomes: Anti-aging/regenerative applications require upregulation, while anticancer applications necessitate suppression of various genes integral to telomere maintenance (e....

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Detalles Bibliográficos
Autores principales: Hong, JinWoo, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563133/
https://www.ncbi.nlm.nih.gov/pubmed/31035374
http://dx.doi.org/10.3390/cells8050392