2-Oxonanonoidal Antibiotic Actinolactomycin Inhibits Cancer Progression by Suppressing HIF-1α

HIF-1 serves as an important regulator in cell response to hypoxia. Due to its key role in promoting tumor survival and progression under hypoxia, HIF-1 has become a promising target of cancer therapy. Thus far, several HIF-1 inhibitors have been identified, most of which are from synthesized chemic...

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Detalles Bibliográficos
Autores principales: Cheng, Jiadong, Hu, Lan, Yang, Zheng, Suo, Caixia, Wang, Yueyang Jack, Gao, Ping, Cui, Chengbin, Sun, Linchong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563139/
https://www.ncbi.nlm.nih.gov/pubmed/31083403
http://dx.doi.org/10.3390/cells8050439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563139/
https://www.ncbi.nlm.nih.gov/pubmed/31083403
http://dx.doi.org/10.3390/cells8050439

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