Cargando…

Nuclear Deformation in Response to Mechanical Confinement is Cell Type Dependent

Mechanosensing of the mechanical microenvironment by cells regulates cell phenotype and function. The nucleus is critical in mechanosensing, as it transmits external forces from the cellular microenvironment to the nuclear envelope housing chromatin. This study aims to elucidate how mechanical confi...

Descripción completa

Detalles Bibliográficos
Autores principales: Doolin, Mary T., Ornstein, Thea S., Stroka, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563141/
https://www.ncbi.nlm.nih.gov/pubmed/31072066
http://dx.doi.org/10.3390/cells8050427