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The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial

High serum levels of gut-derived uremic toxins, especially p-cresyl sulfate (pCS), indoxyl sulfate (IS) and indole acetic acid (IAA), have been linked to adverse outcomes in patients with chronic kidney disease (CKD). Sevelamer carbonate could represent an interesting option to limit the elevation o...

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Detalles Bibliográficos
Autores principales: Bennis, Youssef, Cluet, Yan, Titeca-Beauport, Dimitri, El Esper, Najeh, Ureña, Pablo, Bodeau, Sandra, Combe, Christian, Dussol, Bertrand, Fouque, Denis, Choukroun, Gabriel, Liabeuf, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563242/
https://www.ncbi.nlm.nih.gov/pubmed/31109001
http://dx.doi.org/10.3390/toxins11050279