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Targeting Human Parainfluenza Virus Type-1 Haemagglutinin-Neuraminidase with Mechanism-Based Inhibitors

Human parainfluenza virus (hPIV) infections are a major cause of respiratory tract illnesses in children, with currently no available vaccine or drug treatment. The surface glycoprotein haemagglutinin-neuraminidase (HN) of hPIV has a central role in the viral life cycle, including neuraminic acid-re...

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Detalles Bibliográficos
Autores principales: Eveno, Tanguy, Dirr, Larissa, El-Deeb, Ibrahim M., Guillon, Patrice, von Itzstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563277/
https://www.ncbi.nlm.nih.gov/pubmed/31060278
http://dx.doi.org/10.3390/v11050417