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Bacterial Lipopolysaccharide Induced Alterations of Genome-Wide DNA Methylation and Promoter Methylation of Lactation-Related Genes in Bovine Mammary Epithelial Cells

Bacterial lipopolysaccharide (LPS) could result in poor lactation performance in dairy cows. High methylation of DNA is associated with gene repression. However, it is unclear whether LPS could suppress the expression of lactation-related genes by inducing DNA methylation. Therefore, the objective o...

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Detalles Bibliográficos
Autores principales: Chen, Jingbo, Wu, Yongjiang, Sun, Yawang, Dong, Xianwen, Wang, Zili, Zhang, Zhu, Xiao, Yanli, Dong, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563294/
https://www.ncbi.nlm.nih.gov/pubmed/31137708
http://dx.doi.org/10.3390/toxins11050298