Adeno-Associated Virus VP1u Exhibits Protease Activity

Adeno-associated viruses (AAVs) are being developed for gene delivery applications, with more than 100 ongoing clinical trials aimed at the treatment of monogenic diseases. In this study, the unique N-terminus of AAV capsid viral protein 1 (VP1u), containing a canonical group XIII PLA(2) enzyme doma...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurian, Justin J., Lakshmanan, Renuk, Chmely, William M., Hull, Joshua A., Yu, Jennifer C., Bennett, Antonette, McKenna, Robert, Agbandje-McKenna, Mavis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563295/
https://www.ncbi.nlm.nih.gov/pubmed/31035643
http://dx.doi.org/10.3390/v11050399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563295/
https://www.ncbi.nlm.nih.gov/pubmed/31035643
http://dx.doi.org/10.3390/v11050399

Ejemplares similares