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Parvovirus B19 Uncoating Occurs in the Cytoplasm without Capsid Disassembly and It Is Facilitated by Depletion of Capsid-Associated Divalent Cations

Human parvovirus B19 (B19V) traffics to the cell nucleus where it delivers the genome for replication. The intracellular compartment where uncoating takes place, the required capsid structural rearrangements and the cellular factors involved remain unknown. We explored conditions that trigger uncoat...

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Detalles Bibliográficos
Autores principales: Caliaro, Oliver, Marti, Andrea, Ruprecht, Nico, Leisi, Remo, Subramanian, Suriyasri, Hafenstein, Susan, Ros, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563316/
https://www.ncbi.nlm.nih.gov/pubmed/31083301
http://dx.doi.org/10.3390/v11050430