Standardized Minimal Residual Disease Detection by Next-Generation Sequencing in Multiple Myeloma

Next-generation sequencing (NGS) has been applied to monitor minimal residual disease (MRD) in multiple myeloma (MM). Standardized DNA input and sequencing depth is essential for achieving a uniform sensitivity in NGS-based MRD study. Herein, the sensitivity of 10(−5) was verified by a standardized...

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Detalles Bibliográficos
Autores principales: Yao, Qiumei, Bai, Yinlei, Orfao, Alberto, Chim, Chor Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563351/
https://www.ncbi.nlm.nih.gov/pubmed/31245284
http://dx.doi.org/10.3389/fonc.2019.00449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563351/
https://www.ncbi.nlm.nih.gov/pubmed/31245284
http://dx.doi.org/10.3389/fonc.2019.00449

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