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A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct

BACKGROUND: Altered flow of cerebrospinal fluid (CSF) within the subarachnoid space (SAS) is connected to brain, but also optic nerve degenerative diseases. To overcome the lack of suitable in vitro models that faithfully recapitulate the intricate three-dimensional architecture, complex cellular in...

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Detalles Bibliográficos
Autores principales: Neutzner, Albert, Power, Laura, Dürrenberger, Markus, Scholl, Hendrik P. N., Meyer, Peter, Killer, Hanspeter E., Wendt, David, Kohler, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563372/
https://www.ncbi.nlm.nih.gov/pubmed/31189484
http://dx.doi.org/10.1186/s12987-019-0137-6