Cargando…
A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct
BACKGROUND: Altered flow of cerebrospinal fluid (CSF) within the subarachnoid space (SAS) is connected to brain, but also optic nerve degenerative diseases. To overcome the lack of suitable in vitro models that faithfully recapitulate the intricate three-dimensional architecture, complex cellular in...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563372/ https://www.ncbi.nlm.nih.gov/pubmed/31189484 http://dx.doi.org/10.1186/s12987-019-0137-6 |