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CD8(+) PD-1(+) T-cells and PD-L1(+) circulating tumor cells in chemotherapy-naïve non-small cell lung cancer: towards their clinical relevance?

BACKGROUND: Since tumor cells may escape from immune surveillance through the programmed cell death 1 (PD-1)/programmed death ligand (PD-L)1 axis, this study was designed in order to evaluate whether there is a correlation between the levels of PD-1(+) and PD-L1(+)-expressing immune cells (ICs) and...

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Detalles Bibliográficos
Autores principales: Kotsakis, Athanasios, Kallergi, Galatea, Aggouraki, Despoina, Lyristi, Zaharoula, Koinis, Filippos, Lagoudaki, Eleni, Koutsopoulos, Anastasios, Georgoulias, Vassilis, Vetsika, Eleni-Kyriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563396/
https://www.ncbi.nlm.nih.gov/pubmed/31217824
http://dx.doi.org/10.1177/1758835919853193