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Antiviral RNAi in Insects and Mammals: Parallels and Differences

The RNA interference (RNAi) pathway is a potent antiviral defense mechanism in plants and invertebrates, in response to which viruses evolved suppressors of RNAi. In mammals, the first line of defense is mediated by the type I interferon system (IFN); however, the degree to which RNAi contributes to...

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Detalles Bibliográficos
Autores principales: Schuster, Susan, Miesen, Pascal, van Rij, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563508/
https://www.ncbi.nlm.nih.gov/pubmed/31100912
http://dx.doi.org/10.3390/v11050448