A Peptide‐Induced Self‐Cleavage Reaction Initiates the Activation of Tyrosinase

The conversion of inactive pro‐polyphenol oxidases (pro‐PPOs) into the active enzyme results from the proteolytic cleavage of its C‐terminal domain. Herein, a peptide‐mediated cleavage process that activates pro‐MdPPO1 (Malus domestica) is reported. Mass spectrometry, mutagenesis studies, and X‐ray...

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Detalles Bibliográficos
Autores principales: Kampatsikas, Ioannis, Bijelic, Aleksandar, Pretzler, Matthias, Rompel, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563526/
https://www.ncbi.nlm.nih.gov/pubmed/30825403
http://dx.doi.org/10.1002/anie.201901332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563526/
https://www.ncbi.nlm.nih.gov/pubmed/30825403
http://dx.doi.org/10.1002/anie.201901332

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