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Protease‐activated receptor 2 activates CRAC‐mediated Ca(2+) influx to cause prostate smooth muscle contraction

Protease‐activated receptor 2 (PAR2) is a G‐protein‐coupled receptor that contributes to prostate fibrosis and lower urinary tract symptoms (LUTS). In addition to fibrosis, aberrant smooth muscle tone in the prostate has been hypothesized to play a role. We therefore examined PAR2 expression in prim...

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Detalles Bibliográficos
Autores principales: Paul, Madhumita, Murphy, Stephen F., Hall, Christel, Schaeffer, Anthony J., Thumbikat, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563600/
https://www.ncbi.nlm.nih.gov/pubmed/31198907
http://dx.doi.org/10.1096/fba.2018-00024