Cargando…

Protease‐activated receptor 2 activates CRAC‐mediated Ca(2+) influx to cause prostate smooth muscle contraction

Protease‐activated receptor 2 (PAR2) is a G‐protein‐coupled receptor that contributes to prostate fibrosis and lower urinary tract symptoms (LUTS). In addition to fibrosis, aberrant smooth muscle tone in the prostate has been hypothesized to play a role. We therefore examined PAR2 expression in prim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paul, Madhumita, Murphy, Stephen F., Hall, Christel, Schaeffer, Anthony J., Thumbikat, Praveen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563600/ https://www.ncbi.nlm.nih.gov/pubmed/31198907 http://dx.doi.org/10.1096/fba.2018-00024

Ejemplares similares

A prostate derived commensal Staphylococcus epidermidis strain prevents and ameliorates induction of chronic prostatitis by UPEC infection
por: Murphy, Stephen F., et al.
Publicado: (2018)

Ca(2+) release-activated Ca(2+) (CRAC) current, structure, and function
por: Muik, Martin, et al.
Publicado: (2012)

Paraoxon Attenuates Vascular Smooth Muscle Contraction through Inhibiting Ca(2+) Influx in the Rabbit Thoracic Aorta
por: Zhou, Shouhong, et al.
Publicado: (2010)

Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse
por: Hartzell, Catherine A, et al.
Publicado: (2016)

Single Channel Properties and Regulated Expression of Ca(2+) Release-Activated Ca(2+) (Crac) Channels in Human T Cells
por: Fomina, Alla F., et al.
Publicado: (2000)

Molecular Choreography and Structure of Ca(2+) Release-Activated Ca(2+) (CRAC) and K(Ca2+) Channels and Their Relevance in Disease with Special Focus on Cancer
por: Tiffner, Adéla, et al.
Publicado: (2020)

STIMulating Ca(2+) influx
por: LeBrasseur, Nicole
Publicado: (2006)

Ca2+ influx activated by low pH in Chlamydomonas
Publicado: (1996)

Astrocyte Ca(2+) Influx Negatively Regulates Neuronal Activity
por: Zhang, Yao V., et al.
Publicado: (2017)

Reverse mode Na(+)/Ca(2+ )exchange mediated by STIM1 contributes to Ca(2+ )influx in airway smooth muscle following agonist stimulation
por: Liu, Bo, et al.
Publicado: (2010)

Salvia miltiorrhiza Induces Tonic Contraction of the Lower Esophageal Sphincter in Rats via Activation of Extracellular Ca(2+) Influx
por: Tsai, Ching-Chung, et al.
Publicado: (2015)

Animal Ca(2+ )release-activated Ca(2+ )(CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators
por: Matias, Madeleine G, et al.
Publicado: (2010)

mMCP7, a Mouse Ortholog of δ Tryptase, Mediates Pelvic Tactile Allodynia in a Model of Chronic Pelvic Pain
por: Pattabiraman, Goutham, et al.
Publicado: (2022)

The whole‐cell Ca(2+) release‐activated Ca(2+) current, I (CRAC), is regulated by the mitochondrial Ca(2+) uniporter channel and is independent of extracellular and cytosolic Na(+)
por: Samanta, Krishna, et al.
Publicado: (2019)

Ca(2+) oscillations, Ca(2+) sensitization, and contraction activated by protein kinase C in small airway smooth muscle
por: Mukherjee, Seema, et al.
Publicado: (2013)

Mapping interactions between the CRAC activation domain and CC1 regulating the activity of the ER Ca(2+) sensor STIM1
por: Shrestha, Nisha, et al.
Publicado: (2022)

Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation
por: Grieve, Adam G., et al.
Publicado: (2021)

Excitation-Contraction Coupling in Zebrafish Ventricular Myocardium Is Regulated by Trans-Sarcolemmal Ca(2+) Influx and Sarcoplasmic Reticulum Ca(2+) Release
por: Haustein, Moritz, et al.
Publicado: (2015)

Ca(2+) signaling in T lymphocytes: the interplay of the endoplasmic reticulum, mitochondria, membrane potential, and CRAC channels on transcription factor activation
por: Yang, Pei-Chi, et al.
Publicado: (2020)

¿Cric? ¡Crac! /
por: Danticat, Edwidge, 1969-
Publicado: (1999)

Local Ca(2+) Signaling Domains: The Balancing Act between CRAC Channels and Plasma Membrane Ca(2+) Pumps
por: Petersen, Ole H
Publicado: (2022)

TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex
por: Airiau, Kelly, et al.
Publicado: (2021)

Control of Ca(2+) Influx and Calmodulin Activation by SK-Channels in Dendritic Spines
por: Griffith, Thom, et al.
Publicado: (2016)

Ca(2+) Influx in T Cells: How Many Ca(2+) Channels?
por: Feske, Stefan
Publicado: (2013)

Sustained Contraction in Vascular Smooth Muscle by Activation of L-type Ca(2+) Channels Does Not Involve Ca(2+) Sensitization or Caldesmon
por: Ets, Hillevi K., et al.
Publicado: (2016)

A severe defect in CRAC Ca(2+) channel activation and altered K(+) channel gating in T cells from immunodeficient patients
por: Feske, Stefan, et al.
Publicado: (2005)

Corrigendum: Sustained Contraction in Vascular Smooth Muscle by Activation of L-type Ca(2+) Channels Does Not Involve Ca(2+) Sensitization or Caldesmon
por: Ets, Hillevi K., et al.
Publicado: (2017)

Smooth Muscle Cells of Dystrophic (mdx) Mice Are More Susceptible to Hypoxia; The Protective Effect of Reducing Ca(2+) Influx
por: Uryash, Arkady, et al.
Publicado: (2023)

T cell CRAC dependence
por: Johnston, Nicole
Publicado: (2005)

The elementary unit of store-operated Ca(2+) entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions
por: Luik, Riina M., et al.
Publicado: (2006)

Potentiation of Fc∈ Receptor I–Activated Ca(2+) Current (I(CRAC)) by Cholera Toxin: Possible Mediation by Adp Ribosylation Factor
por: McCloskey, Michael A., et al.
Publicado: (2000)

Purinergic-mediated Ca(2+) influx in Dictyostelium discoideum
por: Ludlow, Melanie J., et al.
Publicado: (2008)

Inhibiting the Ca(2+) Influx Induced by Human CSF
por: Drews, Anna, et al.
Publicado: (2017)

Microdomain Ca(2+) Activation during Exocytosis in Paramecium Cells. Superposition of Local Subplasmalemmal Calcium Store Activation by Local Ca(2+) Influx
por: Erxleben, Christian, et al.
Publicado: (1997)

Functional cooperation between IK(Ca) and TRPC1 channels regulates serum‐induced vascular smooth muscle cell proliferation via mediating Ca(2+) influx and ERK1/2 activation
por: Jia, Xiaoling, et al.
Publicado: (2022)

Regulation of gastric smooth muscle contraction via Ca(2+)-dependent and Ca(2+)-independent actin polymerization
por: Mahavadi, Sunila, et al.
Publicado: (2018)

Endogenous Cardiac Troponin T Modulates Ca(2+)-Mediated Smooth Muscle Contraction
por: Kajioka, Shunichi, et al.
Publicado: (2012)

The effect of the contract-relax-agonist-contract (CRAC) stretch of hamstrings on range of motion, sprint and agility performance in moderately active males: A randomised control trial
por: Burgess, T, et al.
Publicado: (2019)

Proteolytically Activated CRAC Effectors through Designed Intramolecular Inhibition
por: Jazbec, Vid, et al.
Publicado: (2022)

Temperature-dependent STIM1 activation induces Ca(2+) influx and modulates gene expression
por: Xiao, Bailong, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_asv5veh083r3ahh66epips8f7f