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Thymine DNA glycosylase as a novel target for melanoma

Melanoma is an aggressive neoplasm with increasing incidence that is classified by the NCI as a recalcitrant cancer, i.e., a cancer with poor prognosis, lacking progress in diagnosis and treatment. In addition to conventional therapy, melanoma treatment is currently based on targeting the BRAF/MEK/E...

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Detalles Bibliográficos
Autores principales: Mancuso, Pietro, Tricarico, Rossella, Bhattacharjee, Vikram, Cosentino, Laura, Kadariya, Yuwaraj, Jelinek, Jaroslav, Nicolas, Emmanuelle, Einarson, Margret, Beeharry, Neil, Devarajan, Karthik, Katz, Richard A., Dorjsuren, Dorjbal G., Sun, Hongmao, Simeonov, Anton, Giordano, Antonio, Testa, Joseph R., Davidson, Guillaume, Davidson, Irwin, Larue, Lionel, Sobol, Robert W., Yen, Timothy J., Bellacosa, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563616/
https://www.ncbi.nlm.nih.gov/pubmed/30674989
http://dx.doi.org/10.1038/s41388-018-0640-2