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Molecular screening and docking analysis of LMTK3and AKT1 combined inhibitors

The abnormal activation of AKT/mTOR signaling pathway and overexpression of LMTK3, are the main factors involved in the generation of drug resistance. Therefore, the use of computer-aided drug design in the inhibitors discovery offers an advantage to provide new candidates for the treatment of this...

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Detalles Bibliográficos
Autores principales: Allam, Loubna, Fatima, Ghrifi, Wiame, Lakhlili, Hamid, El Amri, Azeddine, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563661/
https://www.ncbi.nlm.nih.gov/pubmed/31223209
http://dx.doi.org/10.6026/97320630014499