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Molecular screening and docking analysis of LMTK3and AKT1 combined inhibitors
The abnormal activation of AKT/mTOR signaling pathway and overexpression of LMTK3, are the main factors involved in the generation of drug resistance. Therefore, the use of computer-aided drug design in the inhibitors discovery offers an advantage to provide new candidates for the treatment of this...
Autores principales: | Allam, Loubna, Fatima, Ghrifi, Wiame, Lakhlili, Hamid, El Amri, Azeddine, Ibrahim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563661/ https://www.ncbi.nlm.nih.gov/pubmed/31223209 http://dx.doi.org/10.6026/97320630014499 |
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