Replacement of an Indole Scaffold Targeting Human 15‐Lipoxygenase‐1 Using Combinatorial Chemistry

Human 15‐lipoxygenase‐1 (15‐LOX‐1) belongs to the class of lipoxygenases, which catalyze oxygenation of polyunsaturated fatty acids, such as arachidonic and linoleic acid. Recent studies have shown that 15‐LOX‐1 plays an important role in physiological processes linked to several diseases such as ai...

Descripción completa

Detalles Bibliográficos
Autores principales: Prismawan, Deka, van der Vlag, Ramon, Guo, Hao, Dekker, Frank J., Hirsch, Anna K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563716/
https://www.ncbi.nlm.nih.gov/pubmed/31231138
http://dx.doi.org/10.1002/hlca.201900040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563716/
https://www.ncbi.nlm.nih.gov/pubmed/31231138
http://dx.doi.org/10.1002/hlca.201900040

Ejemplares similares