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Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination

CD38 is an enzyme that catalyzes the synthesis of cyclic adenosine diphosphate-ribose from nicotinamide adenine dinucleotide (NAD(+)). We recently reported that this molecule regulates the maturation and differentiation of glial cells such as astrocytes and oligodendrocytes (OLs) in the developing b...

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Detalles Bibliográficos
Autores principales: Roboon, Jureepon, Hattori, Tsuyoshi, Ishii, Hiroshi, Takarada-Iemata, Mika, Le, Thuong Manh, Shiraishi, Yoshitake, Ozaki, Noriyuki, Yamamoto, Yasuhiko, Sugawara, Akira, Okamoto, Hiroshi, Higashida, Haruhiro, Kitao, Yasuko, Hori, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563778/
https://www.ncbi.nlm.nih.gov/pubmed/31244614
http://dx.doi.org/10.3389/fncel.2019.00258