Heterozygous Mylk3 Knockout Mice Partially Recapitulate Human DCM With Heterozygous MYLK3 Mutations

Backgrounds: Recent studies identified heterozygous variants in MYLK3 gene that encodes cardiac myosin light chain kinase (cMLCK) are related to familial dilated cardiomyopathy (DCM) for the first time. Autosomal dominant traits suggest that pathogenesis of DCM could be related to heterozygous MYLK3...

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Detalles Bibliográficos
Autores principales: Tougas, Carson L., Grindrod, Tabor, Cai, Lawrence X., Alkassis, Fariz F., Kasahara, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563786/
https://www.ncbi.nlm.nih.gov/pubmed/31244672
http://dx.doi.org/10.3389/fphys.2019.00696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563786/
https://www.ncbi.nlm.nih.gov/pubmed/31244672
http://dx.doi.org/10.3389/fphys.2019.00696

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