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Identification and in vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs With Broad Anti-influenza A Activity

The high genetic variability of influenza A viruses poses a continual challenge to seasonal and pandemic vaccine development, leaving antiviral drugs as the first line of defense against antigenically different strains or new subtypes. As resistance against drugs targeting viral proteins emerges rap...

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Detalles Bibliográficos
Autores principales: Enkirch, Theresa, Sauber, Svenja, Anderson, Danielle E., Gan, Esther S., Kenanov, Dimitar, Maurer-Stroh, Sebastian, von Messling, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563844/
https://www.ncbi.nlm.nih.gov/pubmed/31244822
http://dx.doi.org/10.3389/fimmu.2019.01097