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Identification and in vivo Efficacy Assessment of Approved Orally Bioavailable Human Host Protein-Targeting Drugs With Broad Anti-influenza A Activity
The high genetic variability of influenza A viruses poses a continual challenge to seasonal and pandemic vaccine development, leaving antiviral drugs as the first line of defense against antigenically different strains or new subtypes. As resistance against drugs targeting viral proteins emerges rap...
Autores principales: | Enkirch, Theresa, Sauber, Svenja, Anderson, Danielle E., Gan, Esther S., Kenanov, Dimitar, Maurer-Stroh, Sebastian, von Messling, Veronika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563844/ https://www.ncbi.nlm.nih.gov/pubmed/31244822 http://dx.doi.org/10.3389/fimmu.2019.01097 |
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